Associate Scientist - Cellularization

How you’ll contribute

Develop strategies to cellularize 3D printed scaffolds to generate functional tissue engineered lungs. Create, optimize, and implement analytical metrics that provide insight into the stability and function of printed scaffolding material. Provide expertise on lung tissue engineering methodologies and techniques required to generate a cellularized 3D printed lung scaffold. Support the development of methods and protocols to produce cellularized 3D printed lung constructs which are suitable for pre-clinical and in-vitro functional evaluation.

Key Job Responsibilities

• Actively support or lead efforts to create, develop, and evaluate cellularized 3D printed bioscaffolds for lung tissue engineering
• Establish and maintain a deep understanding of current and emerging technology in lung cell biology, lung physiology, bioscaffold design and lung tissue engineering
• Establish, modify, and improve cell seeding methods to evaluate suitability of 3D printed bioscaffolds for cellularization efforts
• Provide hands-on reduction to practice for manufacturing of prototypes for the Organ Manufacturing program
• Perform cell studies to address technical and scientific challenges to support cellularization of 3D printed scaffolds
• Independently and collaboratively develop and execute molecular and cellular assays to evaluate cell phenotype and function of cellularized 3D printed bioscaffolds
• Independently and collaboratively develop and execute assessments to evaluate gas exchange and perfusibility of cellularized 3D printed bioscaffolds
• Follow existing test practices and develop additional experimental plans to achieve project milestones; understanding and adhering to critical path activities and assembling equipment necessary to execute experimental plans for prototype development
• Conduct (and supervise, if necessary) lab work and prototype performance testing; interpret data and results to provide guidance on design iterations
• Make recommendations and set new directions for assigned projects based on data; testing results and feedback from 3D printing, scaffold design, and bioink development leads
• Perform other duties as assigned